Gregor Brown and Matt Fagerson replace the benched Jonny Gray and injured Jack Dempsey for Scotland’s final Six Nations match away to France on Saturday (20:00 GMT).
Brown starts in the second row while Number 8 Fagerson joins prop brother Zander in the starting XV with Dempsey ruled out with a hamstring injury.
Lock Marshall Sykes, back-rower Ben Muncaster and versatile back Jamie Dobie come into the squad as replacements.
The Scots have two wins so far in this year’s championship.
Scotland: Kinghorn, Graham, Jones, Jordan, Van der Merwe; Russell (co-captain), White; Schoeman, Cherry, Z Fagerson, Brown, Gilchrist, Ritchie, Darge (co-captain), M Fagerson
Replacements: Ashman, Sutherland, Hurd, J Gray, Sykes, Muncaster, Dobie, McDowall.
