Dupont’s France are hoping to leapfrog three-in-a-row chasing Ireland at the top of the table on Saturday ahead of next week’s final round of fixtures.
France, who have lost their past two games against Ireland, have been boosted by fly-half and Dupont’s Toulouse team-mate Romain Ntamack’s return from suspension.
“We know each other very well for a long time now,” added Dupont, who did not play against Ireland last year because of his Olympic Games preparations.
“It’s important for the team as well. He knows the system very well. His difference will be very important tomorrow and I’m sure he will be at his best.”
Ireland, who are chasing the Grand Slam and an unprecedented third successive Six Nations title, have won 29 of their past 31 home games.
“It’s the ultimate challenge in the northern hemisphere to come to Dublin and win, without a shadow of a doubt,” France defence coach Shaun Edwards said.
“The last two years they have been absolutely marvellous and great to watch.
“We have all been preparing hard. I have been listening to Thin Lizzy all week and U2, watching Steve Collins fights from the 90s, so I feel ready!”
