Richie Williams is to leave his role as Cambridge director of rugby after six years with the Championship club.
Williams will step down following the game at Bedford Blues on 28 December.
He led Cambridge to promotion to the second tier of English rugby for the first time in their history in 2023.
“I would like to thank Richie for his hard work, dedication and commitment to Cambridge Rugby during his time here, which has included some of the best moments of success within the club’s history,” said chairman Tim Hague.
Anthony Allen will take on the role of interim head coach following Williams’ departure, assisted by forwards coach Neil Harris.
The club said it would allow them to “review and consider the coaching team options ahead of next season”.
Cambridge won 10 games in a row to secure the National League One title two years ago.
The team have, however, found the step up tough, winning only two of their 20 games in finishing bottom of the Championship last season.
They are next to bottom in the current campaign, with 10 points from eight games, and lost 95-7 to leaders Ealing Trailfinders last weekend.
Williams’ side are next in action on Saturday when they host Ampthill.
