Christian Wade returns to the Newcastle Red Bulls for the visit of play-off chasing Exeter Chiefs to Kingston Park.
Wade, who recently signed a one-year contract extension with Red Bulls will be looking for his first Prem try of the season and the 94th of his career.
Second row Oscar Usher and centre Rhys Beeckmans also come into the team, while loan arrival Ben Healy is named as a replacement.
Exeter centre Nick Lilley is included for his first game since October in a side that includes Newcastle-bound duo Rusi Tuima and Will Rigg.
Second-row Dafydd Jenkins gets the weekend off after playing all but four minutes for Wales across the Six Nations.
Newcastle: E Obatoyinbo; Wade, Hearle, Beeckmans, H Obatoyinbo; Connon, Benitez Cruz; Brocklebank, McGuigan (c), Palframan, Usher, Scott, Parsons, Christie, Leatherbarrow.
Replacements: Fletcher, Hancock, McCallum, Clarke, Gordon, Elliott, Healy, Spencer.
Exeter Chiefs: Woodburn; Brown-Bampoe, Lilley, Rigg, Ridl; Skinner, Varney; Sio, Yeandle (c), Roots, Tuima, Zambonin, Hooper, Vintcent, Fisilau.
Replacements: Heaven, Burger, Tchumbadze, Pearson, Worley-Brady, Cairns, Haydon-Wood, John.
