The Boston Celtics look to stay hot when they take on the injury-plagued Denver Nuggets in a key matchup on Wednesday night. Denver is coming off a 125-124 win at Philadelphia on Monday, while Boston stopped Chicago 115-101 that same night. The Nuggets (24-12), who are second in the Northwest Division, are 14-7 on the road this season. The Celtics (23-12), who are first in the Atlantic Division, are 11-5 on their home court. Jonas Valanciunas (calf), Nikola Jokic (knee) and Cameron Johnson (knee) are all out for Denver. Jamal Murray (ankle), Tim Hardaway Jr. (illness), Aaron Gordon (hamstring) and Christian Braun (ankle) are all questionable.
Tipoff from TD Garden in Boston is set for 7 p.m. ET. The Celtics lead the all-time series 62-40, including wins in eight of the past 11 meetings. Boston is a 9.5-point favorite in the latest Nuggets vs. Celtics odds from DraftKings Sportsbook, while the over/under for total points scored is 232.5. Before making any Nuggets vs. Celtics picks, check out the NBA predictions and betting advice from the SportsLine Projection Model.
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The SportsLine Projection Model simulates every NBA game 10,000 times and has returned well over $10,000 in betting profit for $100 players on its top-rated NBA picks over the past eight-plus seasons. The model enters Week 12 of the 2025-26 NBA season on a sizzling 33-15 roll on top-rated NBA spread picks dating back to last season. Anyone following its NBA betting advice at sportsbooks and on betting apps could have seen huge returns.
Now, the model has simulated Nuggets vs. Celtics 10,000 times and just revealed its coveted NBA picks and betting predictions. You can head to SportsLine now to see the model’s picks. Here are several NBA odds and NBA betting lines for Celtics vs. Nuggets:
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Nuggets vs. Celtics spread: |
Boston -9.5 at DraftKings |
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Nuggets vs. Celtics over/under: |
232.5 points |
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Nuggets vs. Celtics money line: |
Denver +304, Boston -388 |
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Nuggets vs. Celtics picks: |
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Nuggets vs. Celtics streaming: |
Fubo (Try for free) |
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How to make Nuggets vs. Celtics picks
SportsLine’s model is going Over on the total (231.5 points). The total has gone over in four of the last seven head-to-head meetings. The Over has also hit in six of the last eight Nuggets games.
The SportsLine model is projecting Denver’s Jamal Murray — if he’s able to go — to score 24.2 points on average and be one of four Nuggets players to score 11.9 or more points. Boston’s Jaylen Brown, meanwhile, is projected to have 30.1 points as five Celtics players score 11.7 points or more.
It has also generated an against-the-spread pick that hits in nearly 70% of simulations. You can head to SportsLine to see the model’s NBA picks.
So who wins Celtics vs. Nuggets, and which side of the spread hits nearly 70% of the time? Visit SportsLine now to see which side of the Nuggets vs. Celtics spread to back, all from the model that has returned well over $10,000 on top-rated NBA picks, and find out.
