There could be debuts for prop Molly Poolman and second row Becky Boyd who are among the replacements.
Leah Bartlett remains on the bench after her try against Wales.
France also started with a win last weekend, beating Ireland 27-15 in Belfast, and will have a sell-out crowd cheering them on in La Rochelle for Scotland’s visit.
“La Rochelle is some place and I believe it’s sold out,” Easson said. “The whole town will come out – they’ll be there for warm up.
“We have made it very clear to the group of players who have not been in France before what to expect because I think it’s important they understand.”
Scotland came close to an upset in last year’s clash against France, leading 5-3 at half-time before ultimately falling to a 15-5 defeat in Edinburgh.
“France are a good side, but I thought our performance against France last year was excellent,” Easson said. “We’ve got to take confidence in that.
“We’ve got to take confidence from how tight the game was up until the last minute. We’ve got to take confidence from our performance against Wales as well and go in with belief.
“We’ve won 13 out of the past 17 and that’s how we’ve got to look at it. We’ve got to look at you know every game as being a good opportunity.
“It will be tough. We’ve been very, very clear on that, but we’re going there with confidence.”
