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Reading: Spurs vs. Pistons odds, score prediction, time: 2025 NBA picks, Feb. 21 predictions from proven model
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Viascore > Blog > NBA > Spurs vs. Pistons odds, score prediction, time: 2025 NBA picks, Feb. 21 predictions from proven model
NBA

Spurs vs. Pistons odds, score prediction, time: 2025 NBA picks, Feb. 21 predictions from proven model

ViaScore
Last updated: 2025/02/21 at 5:01 PM
ViaScore 5 Min Read
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Contents
Why the Spurs can coverWhy the Pistons can coverHow to make Spurs vs. Pistons picks

The San Antonio Spurs (24-29) will play their second straight game in Austin when they host the Detroit Pistons (29-26) on Friday night. San Antonio was able to overcome the absence of Victor Wembanyama against the Suns after the young superstar was ruled out for the remainder of the season due to a blood clot in his shoulder. The Spurs picked up a 120-109 win, but they are still three games back of Phoenix for 10th place in the Western Conference standings. Detroit is riding a four-game winning streak and is getting set for its first game since the All-Star break. 

Tipoff is set for 8:30 p.m. ET on Friday at the Moody Center in Austin. The Pistons are favored by 4.5 points in the latest Spurs vs. Pistons odds, while the over/under is 233.5 points, per SportsLine consensus. Before entering any Pistons vs. Spurs picks, you’ll want to see the NBA predictions from the model at SportsLine.

The SportsLine Projection Model simulates every NBA game 10,000 times and has returned well over $10,000 in betting profit for $100 players on its top-rated NBA picks over the past six-plus seasons. The model enters the second half of the 2024-25 NBA season on a sizzling 147-104 roll on all top-rated NBA picks dating back to last season, returning nearly $4,000. It’s also an outstanding 18-9 (67%) on top-rated spread picks this season. Anyone following at sportsbooks and on betting apps could have seen huge returns.

The model has set its sights on Detroit-San Antonio. You can head to SportsLine to see its picks. Here are several NBA betting lines for the game:

  • Spurs vs. Pistons spread: Pistons -4.5
  • Spurs vs. Pistons over/under: 233.5 points
  • Spurs vs. Pistons money line: Pistons: -178, Spurs: +149
  • Spurs vs. Pistons picks: See picks here
  • Spurs vs. Pistons streaming: FuboTV (Try for free)

Why the Spurs can cover

San Antonio adapted well without Wembanyama on Thursday night in Austin, beating Phoenix by double digits. Point guard De’Aaron Fox scored 26 points in the win, including 11 in a row in the final 3:18. Keldon Johnson and Julian Champagnie added 15 points each off the bench, while veteran guard Chris Paul had 13 points and 10 assists. 

Wembanyama scored at least 30 points 12 times this season and led the league with 176 blocked shots, so it will take a team effort to replace him. This is the first of two meetings between these teams this season, but San Antonio won twice against Detroit last year. The Spurs have covered the spread in six straight home games against the Pistons and in seven of the last nine head-to-head meetings overall. See which team to pick here. 

Why the Pistons can cover

Detroit returns from the All-Star break with confidence and momentum, riding a four-game winning streak to move into sixth place in the Eastern Conference standings. The Pistons picked up double-digit home victories over the 76ers and Hornets before winning back-to-back games against the Bulls. They set a franchise record with a 42-point halftime lead against Chicago in the first meeting, as shooting guard Malik Beasley scored a team-high 24 points off the bench. 

The Pistons controlled the rematch as well, cruising to a 128-110 win to cover the spread as 6.5-point favorites. Cade Cunningham had 29 points, seven assists and five rebounds, while center Jalen Duren posted a double-double with 16 points and 14 rebounds. The Pistons have covered the spread in 12 of their last 17 road games, and the Spurs have only covered twice in their last seven games. See which team to pick here. 

How to make Spurs vs. Pistons picks

The model has simulated Pistons vs. Spurs 10,000 times and the results are in. We can tell you that the model is leaning Under, and it’s also generated a point-spread pick that is hitting in over 60% of simulations. You can only see the pick at SportsLine.

So who wins Spurs vs. Pistons, and which side of the spread hits over 60% of the time? Visit SportsLine now to see which side of the Pistons vs. Spurs spread you need to jump on, all from the model that is on a 147-104 roll on top-rated NBA picks, and find out.

ViaScore February 21, 2025 February 21, 2025
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