Ireland will play New Zealand at Soldier Field in Chicago on 1 November.
The meeting is a repeat of the 2016 fixture at the same venue when Ireland ended an 111-year wait for a first men’s Test victory over the All Blacks.
Ireland have also played Italy at the home of the National Football League (NFL)’s Chicago Bears, winning 54-7 against the Azzurri in 2018.
“We are delighted to see international rugby return to Chicago for this historic ‘Rematch’ between Ireland and New Zealand,” said Kevin Potts, chief executive of the Irish Rugby Football Union (IRFU).
“The 2016 encounter at Soldier Field is one of the greatest moments in Irish rugby history, and the rivalry that has grown between our two teams since then is a testament to the quality, passion, and the respect that Ireland and New Zealand have for each other.”
The game is expected to be a return to the Ireland coaching box for Andy Farrell after he leads the British and Irish Lions in a three-Test tour of Australia this summer.
Assistant coach Simon Easterby is currently in charge of the team for the Six Nations and will be interim head coach again for Test matches in July.
Ireland have not yet confirmed opposition or dates for those games, or the remainder of their autumn schedule.
